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A serum bottle surrounded by floating spheres on an orange background.Close-up of a person's face with naturally glowing skin.
Bottle and box of Longevity Hybrid Defense Serum on a wooden tray with a towel.

5 Star Reviews

Longevity Hybrid Defense Serum

Our premium serum strengthens your skin’s resilience, restoring a youthful glow. It combats environmental stressors, reduces aging signs, and improves texture and tone for a smoother, more even complexion. 

Science-Driven Formulas
Natural Ingredients
Suitable for any skin type
All Ingredients

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$64.00
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FAQs

Q: Can I use this serum with other products?

A: Yes, it complements other skincare routines. Apply after cleansing and toning, before moisturizing.

Q: Is it suitable for sensitive skin?

A: Yes, our formula is gentle yet effective for all skin types, including sensitive skin.

Hybrid Defense is our science-driven approach, combining potent antioxidants, acai stem cells, and peptides to defend against environmental stressors, rejuvenate skin, and boost radiance—all in one comprehensive formula.

Transformative care, powered by science—where radiant skin meets lasting confidence

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What's Inside

How To Use

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These four forms of vitamin C derivatives—L-ascorbic acid, 3-glyceryl ascorbate, tetrahexyldecyl ascorbate, and magnesium ascorbyl phosphate—work synergistically to provide comprehensive skincare benefits. L-ascorbic acid delivers immediate antioxidant protection and stimulates collagen production, while 3-glyceryl ascorbate hydrates and supports mild antioxidant activity, making it suitable for sensitive skin.


Tetrahexyldecyl ascorbate penetrates deeply into the skin, enhancing collagen synthesis and reducing oxidative stress, and magnesium ascorbyl phosphate offers stable, gentle brightening and anti-aging effects. Together, these derivatives provide a multi-layered approach, ensuring both immediate and sustained skin benefits with enhanced stability, hydration, and anti-aging support, making them practical for a wide range of skin types.

Time to Work
24-Hour Defense
After Effects
Immediate Glow
The Science
Cellular Repair
Experience More
Lasting Resilience
Get Results with
Molecular Damage Repair
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Four Vitamin C’s
Resveratrol
Fulvic Acid with 80 Trace Minerals
Acai Stem Cells
Triple Peptide Complex
Hyaluronic Acid
Pricing
Logo with three overlapping circles and the word 'Meticulous'.
$64/mo
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CE Ferulic
~$182/mo
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C-Firma™ Fresh Day Serum
~$79/mo
Bottle of Longevity Hybrid Defense Serum with dropper, 30ml.

Longevity Hybrid Defense Serum

All Skin Types
Anti-Aging
$64.00
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Precision. Potency. Proven Results.

Science-Driven Formulas 

Pure, Potent Ingredients

Enhanced Bioavailability

Skincare serum box with benefits listed: antioxidant protection, brightening, anti-aging, hydration, and collagen boost.
Your Daily Defense Against Dullness
No more dull, tired skin.
No more uneven skin tone.
No more rough texture.
No more heavy formulas.
5.0
Rated 5.0 out of 5 stars
Based on 14 reviews
Total 5 star reviews: 14 Total 4 star reviews: 0 Total 3 star reviews: 0 Total 2 star reviews: 0 Total 1 star reviews: 0
100%would recommend this product
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14 reviews
  • MS Profile picture for Mario S.
    Mario S.
    I recommend this product
    Rated 5 out of 5 stars
    16 hours ago
    This serum is literally saved my skin

    I was struggling with post acne for so long and after 3 weeks of using hybrid defense serum I started to recognize ACTUAL DIFFERENCE!!! I’m gonna purchase 2 more bottles 😌 thanks guys for creating such a great product

  • KB Profile picture for Kayla B.google logo
    Kayla B.
    Verified Reviewer
    I recommend this product
    Rated 5 out of 5 stars
    2 weeks ago
    Longevity hybrid defense serum

    I’m a licensed Esthetician and I’ve been using this serum for two months now and I love it. I have sensitive skin that is prone to break outs and this product doesn’t irritate my skin at all! It gives my skin a nice glowy look and works under my makeup also. Do yourself a favor and just get this serum!

  • EN Profile picture for Emma N.facebook logo
    Emma N.
    Verified Reviewer
    I recommend this product
    Rated 5 out of 5 stars
    2 days ago
    Must have Longevity Hybrid Defense Serum!

    As a 47 year-old with years of experience using serums I can confidently say that Longevity Hybrid Defense Serum from Meticulous skincare has impressed me. The texture is light and silky, absorbing quickly without feeling greasy. After a few weeks of use my skin feels smoother and more even. It's also helps my dry patches and has never irritated my sensitive skin. This serum has become an essential part of my morning routine, and I'm excited to see continue improvement.

  • AB
    Alexandra B.
    I recommend this product
    Rated 5 out of 5 stars
    1 week ago
    Transformed my skin!

    By far one of the best products I’ve used. Not only did the texture of my skin improve, but it’s much clearer and brighter! I struggle with dry, sensitive skin. This has worked wonders for me and has given me a fresh, dewy, glowy look! Obsessed!

  • W
    Will
    Verified Reviewer
    I recommend this product
    Rated 5 out of 5 stars
    3 weeks ago
    Great product!

    Loved using this product. My skin feels and looks tighter withing just a few weeks of use!

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Science Meets Nature
Our years of discovering globally best of class, whole food, plant-based ingredients that truly provide efficacious results at UB Super led us down this path to create Meticulous Skincare.
Meticulous Skincare combines years of expertise in plant-based innovation with future groundbreaking clinical studies in partnership with Integrated Molecular Therapeutics. Our research, including new initiatives in Brazil, is redefining skincare with supplementation with precision and science at its core.

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