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Bottle and box of Longevity Hybrid Defense Serum on a wooden tray with a towel.

5 Star Reviews

Longevity Hybrid Defense Serum

Our premium serum strengthens your skin’s resilience, restoring a youthful glow. It combats environmental stressors, reduces aging signs, and improves texture and tone for a smoother, more even complexion. 

Science-Driven Formulas
Natural Ingredients
Suitable for any skin type
All Ingredients

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$51.20

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$64.00
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FAQs

Q: Can I use this serum with other products?

A: Yes, it complements other skincare routines. Apply after cleansing and toning, before moisturizing.

Q: Is it suitable for sensitive skin?

A: Yes, our formula is gentle yet effective for all skin types, including sensitive skin.

Hybrid Defense is our science-driven approach, combining potent antioxidants, acai stem cells, and peptides to defend against environmental stressors, rejuvenate skin, and boost radiance—all in one comprehensive formula.

Transformative care, powered by science—where radiant skin meets lasting confidence

Best For

What's Inside

How To Use

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These four forms of vitamin C derivatives—L-ascorbic acid, 3-glyceryl ascorbate, tetrahexyldecyl ascorbate, and magnesium ascorbyl phosphate—work synergistically to provide comprehensive skincare benefits. L-ascorbic acid delivers immediate antioxidant protection and stimulates collagen production, while 3-glyceryl ascorbate hydrates and supports mild antioxidant activity, making it suitable for sensitive skin.


Tetrahexyldecyl ascorbate penetrates deeply into the skin, enhancing collagen synthesis and reducing oxidative stress, and magnesium ascorbyl phosphate offers stable, gentle brightening and anti-aging effects. Together, these derivatives provide a multi-layered approach, ensuring both immediate and sustained skin benefits with enhanced stability, hydration, and anti-aging support, making them practical for a wide range of skin types.

Time to Work
24-Hour Defense
After Effects
Immediate Glow
The Science
Cellular Repair
Experience More
Lasting Resilience
Get Results with
Molecular Damage Repair
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Four Vitamin C’s
Resveratrol
Fulvic Acid with 80 Trace Minerals
Acai Stem Cells
Triple Peptide Complex
Hyaluronic Acid
Pricing
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$64/mo
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Bottle of Longevity Hybrid Defense Serum with dropper, 30ml.

Longevity Hybrid Defense Serum

All Skin Types
Anti-Aging
$64.00
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Precision. Potency. Proven Results.

Science-Driven Formulas 

Pure, Potent Ingredients

Enhanced Bioavailability

Skincare serum box with benefits listed: antioxidant protection, brightening, anti-aging, hydration, and collagen boost.
Your Daily Defense Against Dullness
No more dull, tired skin.
No more uneven skin tone.
No more rough texture.
No more heavy formulas.
5.0
Rated 5.0 out of 5 stars
Based on 23 reviews
Total 5 star reviews: 23 Total 4 star reviews: 0 Total 3 star reviews: 0 Total 2 star reviews: 0 Total 1 star reviews: 0
100%would recommend this product
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23 reviews
  • JO
    Jayleen O.
    Verified Reviewer
    I recommend this product
    Rated 5 out of 5 stars
    1 week ago
    My morning must-have lately!

    This serum has seriously become part of my mom life morning reset. I just put a few drops on before coffee (or during, let’s be real), and it makes my skin feel so fresh and awake. It’s lightweight, not sticky, and gives my face a healthy glow even on 3 hours of sleep. I love how quick and easy it is—because I don’t have time for anything complicated!

  • A Profile picture for Anastasia
    Anastasia
    Verified Reviewer
    I recommend this product
    Rated 5 out of 5 stars
    3 weeks ago
    Science-Backed Skincare That Truly Works

    I recently started using the Meticulous Longevity Hybrid Defense Serum, and I am genuinely impressed! This serum offers a perfect balance between science and nature. It combines potent antioxidants, acai stem cells, and peptides to defend the skin against environmental stressors, rejuvenate it, and boost radiance—all in one powerful formula.

    I appreciate that Meticulous Skincare is committed to providing gentle yet highly effective solutions, without synthetic fragrances, harsh chemicals, or animal testing. The ingredients are hypoallergenic and clinically proven, which is really important for my sensitive skin.

    Since incorporating it into my routine, my skin looks and feels transformed—it’s healthier, more radiant, and noticeably smoother. I also love that the brand focuses on science-driven formulas, pure, potent ingredients, and enhanced bioavailability for better results.

    If you believe that healthy skin is great skin, like Meticulous does, this serum is definitely worth trying. Highly recommend!

  • V
    Valentina
    Verified Reviewer
    I recommend this product
    Rated 5 out of 5 stars
    1 month ago
    The Best serum!

    I have very sensitive, combination skin that becomes especially reactive and prone to breakouts during my menstrual cycle. Finding products that actually soothe and balance my skin — without causing irritation — has always been a challenge.

    From the very first use of the Longevity Hybrid Defense Serum, my skin quite literally thanked me. The texture felt luxurious, lightweight, and calming, and within just a few days, I began to notice real transformation.

    My skin tone became more even, redness noticeably diminished, and even post-acne marks started to fade. It was as if my skin finally found the support it needed to truly heal and glow.

    I’m absolutely in love with this serum — the results speak for themselves. It has become a staple in my skincare routine, and I can genuinely say it’s one of the few products that has exceeded my expectations.

    Thank you so much to Meticulous Skincare for creating something so effective, elegant, and skin-friendly. This is more than just skincare — it’s skin therapy.

  • O
    Olya
    I recommend this product
    Rated 5 out of 5 stars
    1 month ago
    Perfect!!!

    I’ve been using the Longevity Hybrid Defense Serum for a few days now, and I’m already impressed! The texture is lightweight and absorbs quickly without leaving any sticky residue. My skin feels noticeably smoother and more hydrated. I love that it’s packed with antioxidants and peptides – it really feels like it’s giving my skin that extra layer of protection and support. Excited to see the long-term results!

  • TR
    Thaila R.
    Verified Reviewer
    I recommend this product
    Rated 5 out of 5 stars
    1 month ago
    I've finally found it!

    I've finally found it—a complete skincare treatment for my face, all in one bottle. Since I started using the Meticulous Skincare Serum, my routine has become so much simpler yet so much more effective. It feels like this serum understands exactly what my skin needs. Hydration, balance, glow—it delivers everything. My skin has never felt so well taken care of. I’ve upgraded my entire skincare game with just one product—a total game-changer.

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Science Meets Nature
Our years of discovering globally best of class, whole food, plant-based ingredients that truly provide efficacious results at UB Super led us down this path to create Meticulous Skincare.
Meticulous Skincare combines years of expertise in plant-based innovation with future groundbreaking clinical studies in partnership with Integrated Molecular Therapeutics. Our research, including new initiatives in Brazil, is redefining skincare with supplementation with precision and science at its core.

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